This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Located throughout the pre-mRNA are short, cis-acting ...

A study across 26 mammals reveals that alternative RNA splicing strongly correlates with maximum lifespan. Brain tissue ...

To carry out all of life’s functions, proteins must be produced from instructions carried by genes within DNA and delivered to the cell’s protein-making machinery by messenger RNA. However, to ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger RNA—a prerequisite for protein synthesis in the cell. The poorly ...

Researchers have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. They explain what makes ...

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...

TAMPA, Fla. — Pancreatic cancer presents a challenging prognosis, marked by a five-year overall survival rate of merely 12.5%. Diagnosis frequently occurs at an advanced stage, characterized by ...

• Pre-mRNA splicing is an essential step for the regulation of gene expression. In order to specifically capture splicing variants in plants for genome-wide association studies (GWAS), we developed a ...

A recent study by TUS researchers reveal that the Cpeb4 protein may have a role in regulating osteoclast differentiation. This, in turn, could lead to the development of new therapeutic drugs for ...