Investigators have two important questions to consider when evaluating microarray expression data. First, they must ask whether the results are valid—in other words, accurate—for the particular ...

We used cDNA microarrays to monitor changes in gene expression profiles induced by ionizing radiation in mouse total blood. The subsets of genes best characterizing each dose were identified by ...

No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2004 ASCO Annual Meeting. This abstract does not include a full text component.

The Nottingham Prognostic Index (NPI) applied to 467 patients (pts) with a long-term follow-up that were treated in a single institution No significant financial relationships to disclose. This is an ...

Researchers at the National Institute on Aging will distribute a recently established mouse cDNA microarray/clone set containing 7,407 unique genes to 20 designated academic centers worldwide. The new ...

The bound cDNA indicates a gene that is expressed because the complimentary partner strands are already within the microarray. Any unbound cDNA can be washed off the microarray so only the bound, ...

Application of gene expression technology to cancer pharmacology and drug discovery is particularly challenging because most clinical tumour specimens have complex and imperfect treatment histories.

A significant limitation to the analytical accuracy and precision of dual-labeled spotted cDNA microarrays is the signal error due to dye bias. Transcript-dependent ...

*These authors contributed equally to the preparation of this manuscript. Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility, ...

You are oncologists specializing in breast cancer and will be conducting a microarray analysis on one of two newly diagnosed breast cancer patients, Mrs. Jones and Mrs. Brown. You will be adding a ...

In this issue we take a close look at DNA microarrays, the current amore of biological and biomedical researchers. There's little reason to doubt that the infatuation will continue, at least for ...

The field of proteomics has undergone rapid advancements over the last decade and protein microarrays have emerged as a promising technological platform for the challenging task of studying complex ...