Restoring P53's autonomous anti-cancer function through P53 mRNA delivery is a promising anti-tumor strategy. Yet, in tumors harboring mutant P53, the existing mutant P53 (Mutp53) would interferes ...

A KAIST research team led by Professor Won Do Heo (Department of Biological Sciences) has developed an optogenetic platform, RELISR (REversible LIght-induced Store and Release), that enables precise ...

For the very first time, a study led by Julian Chen and his group in Arizona State University’s School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution, has ...

Targeting mRNA expression presents a promising approach in the treatment of haploinsufficiency disorders, offering a new avenue for therapeutic intervention. While gene expression changes are commonly ...