MIT researchers have developed a new way to study the function of microRNA, tiny strands of genetic material that help regulate at least 25 percent of a cell's genes. The new technique could shed ...

PHILADELPHIA -- Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does ...

The authors provide further insight into microRNA biology, and the simplicity of anti-miR oligonucleotide drug delivery. RNA-based therapeutics hold significant potential as promising treatment ...

Comparative effectiveness of treatment strategies for urothelial cancer of the bladder (UCB) with clinical lymph node involvement (cN+). Anti-tumor activity, safety and pharmacokinetics (PK) of AGS15E ...

Phase II trial of the oral mTOR inhibitor everolimus (RAD001) for patients with relapsed or refractory lymphoma Mantle Cell Lymphoma (MCL) represents only 5–10% of all non-Hodgkins lymphomas, making ...

Dr. Yogesh Dwivedi authored a book chapter “microRNA Function and Dysregulation in Depression and Suicide” in Suicide Phenomenology and Neurobiology, Edited by: Keri Cannon and Thomas Hudzik.

Nibbler (Nbr) is a 3′-to-5′ exoribonuclease whose catalytic 3′-end trimming activity impacts microRNA (miRNA) and PIWI-interacting RNA (piRNA) biogenesis. Here, we report on structural and functional ...

Roula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter. US scientists Victor Ambros and Gary Ruvkun have won the medicine Nobel Prize for discovering tiny molecules ...