The phosphorylation of proteins in eukaryotic cells is a key post-translational modification that regulates essential and diverse biological phenomena. Phosphorylation is installed by protein kinases ...

Proteins participate in various biological processes and can be harnessed to probe and control biological events selectively and reproducibly, but the genetic code limits the building block to 20 ...

Instead of fixing one of the many genes that can be mutated, the technique addresses a type of mutation they share, a stop ...

The process of endosymbiont integration into a host to become an organelle results in a combination of gene loss, transfer to the nucleus, and retention in the organellar genome. It is unclear why ...

Interestingly, the mutation T552I appears to represent an evolutionarily differentiated residue within the CC2 domain, comprising Thr in the majority of plants and animals, Ile in most fungi, and Ile ...

A molecule called tRNA, or transfer ribonucleic acid, is an essential component of the human genome that acts as a translator. It reads the genetic code and translates it into proteins - one of the ...

The genome contains many different kinds of sequences; some genetic sequences are regulatory, some have no apparent function, and others are coding regions that are used to generate proteins. To do so ...

Aminoacyl-tRNA synthetases (aaRSs) are ancient and evolutionary conserved enzymes catalyzing the formation of aminoacyl-tRNAs, that are used as substrates for ribosomal protein biosynthesis. In ...

This is a preview. Log in through your library . Abstract The first committed step of porphyrin synthesis in higher plants is the reduction of glutamyl-tRNA to glutamate 1-semialdehyde. This reaction ...

A molecule called tRNA is an essential component of the human genome that acts as a translator. When researchers and clinicians investigate the genome's relation to disease, they have traditionally ...