The phosphorylation of proteins in eukaryotic cells is a key post-translational modification that regulates essential and diverse biological phenomena. Phosphorylation is installed by protein kinases ...

During translation, the ribosome progressively coordinates the dynamic interplay of tRNA and protein factors to decipher individual codons of an mRNA molecule and synthesize protein. The ribosome ...

The genome contains many different kinds of sequences; some genetic sequences are regulatory, some have no apparent function, and others are coding regions that are used to generate proteins. To do so ...

A molecule called tRNA, or transfer ribonucleic acid, is an essential component of the human genome that acts as a translator. It reads the genetic code and translates it into proteins - one of the ...

A molecule called tRNA is an essential component of the human genome that acts as a translator. When researchers and clinicians investigate the genome's relation to disease, they have traditionally ...

Documenting the first substantial thing I did in my own lab at CU, discovery of the ability of Aminoacyl RNA Synthetases (AARS) to correct aminoacylation mistakes (simultaneous with Eldred & Schimmel, ...

This is a preview. Log in through your library . Abstract The first committed step of porphyrin synthesis in higher plants is the reduction of glutamyl-tRNA to glutamate 1-semialdehyde. This reaction ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, No. 26 (Dec. 23, 1997), pp. 14383-14388 (6 pages) Lysyl-tRNAs are essential for protein biosynthesis by ...

Instead of fixing one of the many genes that can be mutated, the technique addresses a type of mutation they share, a stop ...

For disorders driven by a known genetic component, research understandably focuses on developing a drug targeting that genetic signature. When that works, the outcome benefits patients but the end ...

Scientists say that the availability of a trace nutrient can cause genome-wide changes to how organisms encode proteins.The use of queuine, which is produced by bacteria and absorbed in the gut, ...