Characterizing clonal evolution in blood cancers like acute myeloid leukemia (AML) is critical for understanding their mutational histories and how cell populations change during disease development.

Mudras in Medicine: A Role for Dance in Appreciating Nonverbal Communication in the Clinical Encounter The risk of sMN in AA is associated with disease severity, lack of response to treatment, and ...

The study is among the first to look at the potential impacts of clonal dynamics on patients with lower-risk myelodysplastic syndromes (MDS). However, most of what scientists know about the impact of ...

A review examines the prevailing theory of cancer evolution. The authors highlight both practical and theoretical limitations of the clonal model of cancer evolution and propose areas for improving ...

Like Plato’s description of the enigma of human existence, stem cells may remain dormant for a person’s life span and never fulfill their potential — that is, “never come to be” — or may differentiate ...

Panelists discuss how early relapse in standard-risk patients represents a failure of current risk assessment methods and may require advanced sequencing technologies to identify hidden high-risk ...

Tumor-infiltrating clonal hematopoiesis increased the risk of disease recurrence or death among patients with cancer. TET2 mutations were the strongest genetic predictor of tumor-infiltrating clonal ...

This article examines some of the cell-based approaches that researchers are using to study acquired drug resistance and the ...

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer ...