Europe PMC

Single sarcomere contraction dynamics in a whole muscle.

The instantaneous sarcomere length (SL) is regarded as an important indicator of the functional properties of striated muscle. Previously, we found greater sarcomere elongations at the distal end ...
eLife

Stochastic tug-of-war among sarcomeres mediates cardiomyocyte response to environmental stiffness

This study provides a valuable characterization of individual sarcomere's contractility and synchrony in spontaneously beating cardiomyocytes as a function of substrate stiffness. The authors, however ...
Frontiers

Role of Active Contraction and Tropomodulins in Regulating Actin Filament Length and Sarcomere Structure in Developing Zebrafish Skeletal Muscle

Dechorionated wild-type embryos were transferred into Embryo Medium (5 mM NaCl, 0.17 mM KCl, 0.33 mM CaCl 2, and 0.33 mM MgSO 4, pH 6.8–6.9) supplemented with 0.03% Tricaine (Tricaine methanesulfonate ...
Frontiers

A multiscale chemo-electro-mechanical skeletal muscle model to analyze muscle contraction and force generation for different muscle fiber arrangements

1 Continuum Biomechanics and Mechanobiology Research Group, Institute of Applied Mechanics (CE), University of Stuttgart, Stuttgart, Germany 2 Stuttgart Research Center for Simulation Technology ...
istockphoto

Sarcomere stock illustrations

Sarcomere showing the location of the I band, A band, H band, M line, and Z lines. Structure of Cardiac muscle fibers. anatomy of cardiomyocyte. Structure of Cardiac muscle fibers. anatomy of ...
GitHub

A Python package for comprehensive analysis of sarcomere structure and function in cardiomyocytes

SarcAsM (Sarcomere Analysis Multitool) is an AI-powered Python package for cardiomyocyte sarcomere analysis. It enables precise multilevel structural and functional assessment of sarcomeres in ...