NFL teams have until 4 p.m. EDT on Tuesday to trim their rosters down to 53 players, and tonight’s game represents the last meaningful opportunity for those players on the roster bubble to make a great impression on general manager Brandon Beane and head coach Sean McDermott in their bid to earn a roster spot.

The Buffalo Bills will round out their 2025 NFL preseason schedule against the Tampa Bay Buccaneers. The Saturday contest at Raymond James Stadium will feature many backups both due to injury and the Bills just deciding not to risk starting players such as quarterback Josh Allen.