With last-minute concessions and stark warnings from Trump, the Republican holdouts largely dropped their opposition to salvage the “One Big Beautiful Bill” that’s central to the GOP agenda. The House launched debate before midnight and by dawn the vote was called, 215-214, with Democrats staunchly opposed. It next goes to the Senate.

House Republicans passed a sweeping domestic policy bill early Thursday morning that would enshrine much of President Trump’s agenda into law.

The legislation would slash taxes, steer more money to the military and border security, and pay for some of this with cuts to Medicaid, food assistance, education and clean energy programs, adding s...