Abstract With the biological relevance of the whole cells, low cost compared with animal experiments, a wide variety of cell-based screening platforms (cell-based assay, cell-based …

May 24, 2025 · The field of drug development has seen significant advancements in recent years, primarily driven by the development of advanced preclinical models. Traditional drug screening …

Mar 10, 2023 · The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical research based on biologically accurate screening approaches. Since …

Introduction Pharmaceutical companies approach drug discovery in a variety of ways. An early part of the experimental process often involves screening a large number of compounds using …

Oct 1, 2020 · High-throughput screening (HTS) provides starting chemical matter in the adventure of developing a new drug. In this review, we survey several HTS methods used today for hit …

Nov 5, 2025 · This article explores how advances in automation, 3D cell models and AI are transforming high-throughput screening, driving faster and more predictive drug discovery.

Cell-based assays are crucial across various stages of drug discovery, from initial screening and hit identification to lead optimization and safety assessments. They allow for the evaluation of …

May 10, 2019 · Microfluidics is an appealing platform for drug screening and discovery. Compared with the conventional drug screening methods based on Petri dishes and …

Therapeutically relevant cell-based assays for drug discovery and development Cell-based assays provide a relevant biological context, making them crucial for discovery and development. Our …

Integrating advanced microscopy with cell-based assays is attractive because cellular events can be monitored with both spatial and temporal resolution. This approach has driven the …