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Dec 20, 2024 · Monoclonal gammopathy of undetermined significance occurs most often in older men. MGUS usually causes no problems. But sometimes it can lead to more-serious diseases. …

MGUS does not usually cause symptoms, so it doesn’t need to be treated. Since MGUS may lead to a more serious condition, regular monitoring and checkups are recommended throughout your life. This often includes regular physical exams and blood tests. This will help find problems as …

MGUS can sound alarming, especially when you first see the words “monoclonal protein” on a lab report.↵ Many people learn about MGUS only because a doctor ordered blood tests for another …

Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia in which plasma cells or other types of antibody-producing cells secrete a myeloma protein, i.e. an …

Monoclonal gammopathy of undetermined significance, or MGUS, is a blood disorder that occurs when bone marrow in the body produces abnormal plasma cells. Similar to multiple myeloma, …

Healthcare providers consider MGUS a “benign precursor” to a blood cancer called multiple myeloma or one of several other conditions. This means that although MGUS isn’t cancer, it …

Oct 7, 2025 · With MGUS, a type of white blood cell called a plasma cell makes too much of the "M" (for "monoclonal") protein in the blood. Most people with MGUS are fine for many years. …

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